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Complementary feed whose combination of nutrients helps maintain normal cognitive function in dogs and cats.

Descripción del producto
  • Chicken protein-free
  • Without preservatives.
  • No artificial colorings
  • Suitable modes of use according to the weight of the pet
  • Easily divisible tablets.

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Chicken protein-free
Without preservatives.
Easily divisible tablets.
Easily divisible tablets.



Essential nucleotide in the biosynthesis of phospholipids and glycolipids in cell membranes, such as neurons.

Dried apple pulp

Provides polyphenols and quinones.


Precursor of the neurotransmitter Serotonin, essential for mood regulation, behavior, and anxiety.


Contributes to the normal functioning of the nervous system and normal psychological function.

Selenium and Zinc

Contribute to cellular protection against oxidative damage.

Barley bran

Aporta Astaxantina y Omega 3.



Box with 60 tablets, in blister packs of 10 tablets each.

Box with 60 tablets, in blister packs of 10 tablets each.

What are the instructions for use?


1 tablet per day.

  • Up to 10 kg: 1 tablet per day.
  • 10 to 20 kg: 2 tablets per day.
  • 20 to 30 kg: 3 tablets per day.
  • 30 to 40 kg: 4 tablets per day.
  • Over 40 kg: 5 tablets per day.
Otras indicaciones

Oral route

If preferred, mix with the usual food.

As it is a dietary supplement, it can be administered continuously.

Cognitive Dysfunction in Dogs and Cats

Cognitive Dysfunction Syndrome (CDS) in cats and dogs is a clinical condition that affects older pets, characterized by a series of neurological disorders that negatively impact their cognitive functions, changes in behavior, social interactions, and quality of life.

Clinical signs include:

  • Changes in interaction with owners or other animals.
  • Disorientation and confusion, anxiety, and restlessness.
  • Sleep-wake cycle disorders, changes in behavior patterns.
  • Alterations in daily routines.
  • Changes in motor function.

CDS has become an increasingly important area of research and veterinary care. Early diagnosis and appropriate intervention are key to addressing this syndrome.

Factors Associated with Cognitive Dysfunction Syndrome in Dogs and Cats

CDS manifests in various ways:

  • Macroscopic changes in the brain: cortical atrophy, which affects areas of the brain related to memory and learning, as well as the hippocampus, a structure that contributes to the formation of new memories.
  • Neuronal changes: such as the loss of nerve cells in key brain areas.
  • Oxidative damage and inflammation: leading to the deterioration of proteins, lipids, and nucleotides in the brain, eventually resulting in neuron death.
  • Accumulation of ß-amyloid protein: may contribute to neuronal loss and brain atrophy.

CDS can also result from cerebrovascular pathologies: cerebral vascular changes, gliosis, and ventricular dilation, leading to cerebral atrophy, ventricular enlargement, and lesions in the medial temporal lobes.

How the nutrients in the complementary food Cognidine® help pets

Cognidine® provides nutrients to help:

Maintain the cognitive system of senior dogs and cats.

Consult your veterinarian banner

"At Pharmadiet, we encourage all pet owners to maintain a close relationship with their trusted veterinarian.

egular consultations with veterinary professionals are fundamental for preventive care, early diagnosis of health problems, and planning appropriate treatments.

Through our close collaboration with these experts, we work together to keep your animal companions in their best health, ensuring a full and active life for them."


  1. Wattig B et al. Acceleration of nerve and muscle regeneration by administration of nucleotides–electroneurophysiological and morphometrical investigations. Acta Histochem Suppl. 1992;42:333-9.
  2. Chen TH et al. A nucleoside-nucleotide mixture may reduce memory deterioration in old senescence-accelerated mice. . J Nutr. 2000 Dec;130(12):3085-9.
  3. Harris CB. Dietary pyrroloquinoline quinone (PQQ) alters indicators of inflammation and mitochondrial-related metabolism in human subjects.1. J Nutr Biochem. 2013 Dec;24(12):2076-84.
  4. He B. Effects of pyrroloquinoline quinine on oxidative stress- induced apoptosis of Schwann cells and its mechanism. Zhonghua Zheng Xing Wai Ke Za Zhi. 2014 Mar;30(2):111-7
  5. Silber BY. Effects of tryptophan loading on human cognition, mood, and sleep. Neuroscience and Biobehavioral Reviews .2010; 34: 387–407.
  6. Jean S. DeNapoli. Effect of dietary protein content and tryptophan supplementation on dominance aggression, territorial aggression, and hyperactivity in dogs. 2000; JAVMA, Vol 217, No. 4.
  7. Murphy T, et al. Effects of diet on brain plasticity in animal and human Studies: mind the gap. Neural Plasticity.2014; ID 563160.

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Pharmadiet Veterinary is a brand specialized in complementary feeds for animals and products for the hygiene, care, and management of animals for animal health with over 30 years of experience

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Pharmadiet Veterinaria es una marca especializada en suplementos alimentarios para animales y productos para la higiene, cuidado y manejo de los animales para la salud animal con más de 30 años de experiencia

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© Pharmadiet Veterinary is a brand of the OPKO group | All rights reserved.
Web design and digital marketing by Wide Marketing

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